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Crucial Role of TSC-22 in Preventing the Proteasomal Degradation of p53 in Cervical Cancer
The p53 tumor suppressor function can be compromised in many tumors by the cellular antagonist HDM2 and human papillomavirus oncogene E6 that induce p53 degradation. Restoration of p53 activity has strong therapeutic potential. Here, we identified TSC-22 as a novel p53-interacting protein and show i...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411576/ https://ncbi.nlm.nih.gov/pubmed/22870275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042006 |
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