Crucial Role of TSC-22 in Preventing the Proteasomal Degradation of p53 in Cervical Cancer

The p53 tumor suppressor function can be compromised in many tumors by the cellular antagonist HDM2 and human papillomavirus oncogene E6 that induce p53 degradation. Restoration of p53 activity has strong therapeutic potential. Here, we identified TSC-22 as a novel p53-interacting protein and show i...

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Detaylı Bibliyografya
Asıl Yazarlar: Yoon, Cheol-Hee, Rho, Seung Bae, Kim, Seong-Tae, Kho, Seongho, Park, Junsoo, Jang, Ik-Soon, Woo, Seonock, Kim, Sung Soon, Lee, Je-Ho, Lee, Seung-Hoon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411576/
https://ncbi.nlm.nih.gov/pubmed/22870275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042006
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