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PKR, a p53 target gene, plays a crucial role in the tumor-suppressor function of p53
Type I IFN-induced expression of dsRNA-activated protein kinase (PKR) during viral infection is a well-established antiviral mechanism. However, little is known about the expression of PKR in the context of p53 and about PKR involvement in p53-mediated tumor suppression. Here, we report that PKR is...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683089/ https://ncbi.nlm.nih.gov/pubmed/19416861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812148106 |
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