Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells

The tumor suppressor protein p53 is unstable in quiescent cells and undergoes proteosomal degradation. Under conditions of cellular stress, p53 is rapidly stabilized by post-translational modification, thereby escaping degradation and translocating to the nucleus where it activates genes related to...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ahn, Hee-Jin, Kim, Kwang-Soo, Shin, Kyung-Won, Lim, Kee-Hwan, Kim, Jin-Ock, Lee, Je-Yong, Kim, Jiewan, Park, Ji-Hoon, Yang, Kyung-Min, Baek, Kwang-Hyun, Ko, Jeong-Jae, Park, Kyung-Soon
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792573/
https://ncbi.nlm.nih.gov/pubmed/26540344
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados