Aberrantly upregulated TRAP1 is required for tumorigenesis of breast cancer

Tumor necrosis factor receptor-associated protein 1 (TRAP1) is abnormally expressed in many cancers. In this study, we showed that TRAP1 is aberrantly upregulated in breast tumors compared to control tissues. TRAP1 knockdown downregulates mitochondrial aerobic respiratory, sensitizes cells to lethal...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Zhang, Bo, Wang, Jing, Huang, Zhen, Wei, Peng, Liu, Ying, Hao, Junfeng, Zhao, Lijing, Zhang, Fenglin, Tu, Yaping, Wei, Taotao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792571/
https://ncbi.nlm.nih.gov/pubmed/26517089
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