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244-MPT overcomes gefitinib resistance in non-small cell lung cancer cells

The epidermal growth factor receptor (EGFR) is known to play a critical role in non-small cell lung cancer(NSCLC). Several EGFR tyrosine kinase inhibitors(TKIs), such as gefitinib, have been used as effective clinical therapies for patients with NSCLC. Unfortunately, acquired resistance to gefitinib...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Zhang, Yi, Yao, Ke, Shi, Chengcheng, Jiang, Yanan, Liu, Kangdong, Zhao, Song, Chen, Hanyong, Reddy, Kanamata, Zhang, Chengjuan, Chang, Xiaoyu, Ryu, Joohyun, Bode, Ann M., Dong, Ziming, Dong, Zigang
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792556/
https://ncbi.nlm.nih.gov/pubmed/26517520
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