Growth-arrest-specific 7C protein inhibits tumor metastasis via the N-WASP/FAK/F-actin and hnRNP U/β-TrCP/β-catenin pathways in lung cancer

Growth-arrest-specific 7 (GAS7) belongs to a group of adaptor proteins that coordinate the actin cytoskeleton. Among human GAS7 isoforms, only GAS7C possesses a Src homology 3 domain. We report here that GAS7C acts as a migration suppressor and can serve as a prognostic biomarker in lung cancer. GAS...

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Publicado en:Oncotarget
Autores principales: Tseng, Ruo-Chia, Chang, Jer-Wei, Mao, Jiou-Shan, Tsai, Charng-Dar, Wu, Pei-Chen, Lin, Cuei-Jyuan, Lu, Yi-Lin, Liao, Sheng-You, Cheng, Hung-Chi, Hsu, Han-Shui, Wang, Yi-Ching
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792552/
https://ncbi.nlm.nih.gov/pubmed/26506240
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