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Enhancement of adoptive T cell transfer with single low dose pretreatment of doxorubicin or paclitaxel in mice
Ex vivo expansion of CD8(+) T-cells has been a hindrance for the success of adoptive T cell transfer in clinic. Currently, preconditioning with chemotherapy is used to modulate the patient immunity before ACT, however, the tumor microenvironment beneficial for transferring T cells may also be damage...
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| Publié dans: | Oncotarget |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792547/ https://ncbi.nlm.nih.gov/pubmed/26683520 |
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