Enhancement of adoptive T cell transfer with single low dose pretreatment of doxorubicin or paclitaxel in mice

Ex vivo expansion of CD8(+) T-cells has been a hindrance for the success of adoptive T cell transfer in clinic. Currently, preconditioning with chemotherapy is used to modulate the patient immunity before ACT, however, the tumor microenvironment beneficial for transferring T cells may also be damage...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Hsu, Fei-Ting, Chen, Tzu-Chun, Chuang, Hui-Yen, Chang, Ya-Fang, Hwang, Jeng-Jong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper: Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792547/
https://ncbi.nlm.nih.gov/pubmed/26683520
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