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Serial Low Doses of Sorafenib Enhance Therapeutic Efficacy of Adoptive T Cell Therapy in a Murine Model by Improving Tumor Microenvironment

Requirements of large numbers of transferred T cells and various immunosuppressive factors and cells in the tumor microenvironment limit the applications of adoptive T cells therapy (ACT) in clinic. Accumulating evidences show that chemotherapeutic drugs could act as immune supportive instead of imm...

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Main Authors: Chuang, Hui-Yen, Chang, Ya-Fang, Liu, Ren-Shyan, Hwang, Jeng-Jong
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198194/
https://ncbi.nlm.nih.gov/pubmed/25333973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109992
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