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Spatial separation of the processing and MHC class I loading compartments for cross-presentation of the tumor-associated antigen HER2/neu by human dendritic cells
Cross-presentation is the process by which professional antigen presenting cells (APCs) (B cells, dendritic cells (DCs) and macrophages) present endocytosed antigens (Ags) via MHC-I to CD8(+) T cells. This process is crucial for induction of adaptive immune responses against tumors and infected cell...
Tallennettuna:
| Julkaisussa: | Oncoimmunology |
|---|---|
| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792485/ https://ncbi.nlm.nih.gov/pubmed/26985398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1047585 |
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