Spatial separation of the processing and MHC class I loading compartments for cross-presentation of the tumor-associated antigen HER2/neu by human dendritic cells

Cross-presentation is the process by which professional antigen presenting cells (APCs) (B cells, dendritic cells (DCs) and macrophages) present endocytosed antigens (Ags) via MHC-I to CD8(+) T cells. This process is crucial for induction of adaptive immune responses against tumors and infected cell...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Baleeiro, Renato B, Rietscher, René, Diedrich, Andrea, Czaplewska, Justyna A, Lehr, Claus-Michael, Scherließ, Regina, Hanefeld, Andrea, Gottschaldt, Michael, Walden, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
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Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792485/
https://ncbi.nlm.nih.gov/pubmed/26985398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1047585
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