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Biglycan-mediated upregulation of MHC class I expression in HER-2/neu-transformed cells
The extracellular matrix protein biglycan (BGN) has oncogenic or tumor suppressive potential depending on the cellular origin. HER-2/neu overexpression in murine fibroblasts and human model systems is inversely correlated with BGN expression. Upon its restoration BGN(high) HER-2/neu(+) fibroblasts w...
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| Publicado no: | Oncoimmunology |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889282/ https://ncbi.nlm.nih.gov/pubmed/29632715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1373233 |
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