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HER-2/neu-mediated Down-regulation of Biglycan Associated with Altered Growth Properties
The extracellular matrix protein biglycan (Bgn) is a leucine-rich proteoglycan that is involved in the matrix assembly, cellular migration and adhesion, cell growth, and apoptosis. Although a distinct expression of Bgn was found in a number of human tumors, the role of this protein in the initiation...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397858/ https://ncbi.nlm.nih.gov/pubmed/22582394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334425 |
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