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HER-2/neu-mediated Down-regulation of Biglycan Associated with Altered Growth Properties

The extracellular matrix protein biglycan (Bgn) is a leucine-rich proteoglycan that is involved in the matrix assembly, cellular migration and adhesion, cell growth, and apoptosis. Although a distinct expression of Bgn was found in a number of human tumors, the role of this protein in the initiation...

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Detalhes bibliográficos
Main Authors: Recktenwald, Christian V., Leisz, Sandra, Steven, André, Mimura, Kousaku, Müller, Anja, Wulfänger, Jens, Kiessling, Rolf, Seliger, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397858/
https://ncbi.nlm.nih.gov/pubmed/22582394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334425
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