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Genetic Evidence for the Coordinated Regulation of Collagen Fibrillogenesis in the Cornea by Decorin and Biglycan

Decorin and biglycan are class I small leucine-rich proteoglycans (SLRPs) involved in regulation of collagen fibril and matrix assembly. We hypothesize that tissue-specific matrix assembly, such as in the cornea, requires a coordinate regulation involving multiple SLRPs. To this end, we investigated...

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Detalhes bibliográficos
Main Authors: Zhang, Guiyun, Chen, Shoujun, Goldoni, Silvia, Calder, Bennett W., Simpson, Holly C., Owens, Rick T., McQuillan, David J., Young, Marian F., Iozzo, Renato V., Birk, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659246/
https://ncbi.nlm.nih.gov/pubmed/19136671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806590200
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