TRPM4-dependent post-synaptic depolarization is essential for the induction of NMDA receptor-dependent LTP in CA1 hippocampal neurons

TRPM4 is a calcium-activated but calcium-impermeable non-selective cation (CAN) channel. Previous studies have shown that TRPM4 is an important regulator of Ca(2+)-dependent changes in membrane potential in excitable and non-excitable cell types. However, its physiological significance in neurons of...

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Udgivet i:Pflugers Arch
Main Authors: Menigoz, Aurélie, Ahmed, Tariq, Sabanov, Victor, Philippaert, Koenraad, Pinto, Silvia, Kerselaers, Sara, Segal, Andrei, Freichel, Marc, Voets, Thomas, Nilius, Bernd, Vennekens, Rudi, Balschun, Detlef
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
Fag:
Ion Channels, Receptors and Transporters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792339/
https://ncbi.nlm.nih.gov/pubmed/26631168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-015-1764-7
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