Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity

Steviol glycosides (SGs), such as stevioside and rebaudioside A, are natural, non-caloric sweet-tasting organic molecules, present in extracts of the scrub plant Stevia rebaudiana, which are widely used as sweeteners in consumer foods and beverages. TRPM5 is a Ca(2+)-activated cation channel express...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Philippaert, Koenraad, Pironet, Andy, Mesuere, Margot, Sones, William, Vermeiren, Laura, Kerselaers, Sara, Pinto, Sílvia, Segal, Andrei, Antoine, Nancy, Gysemans, Conny, Laureys, Jos, Lemaire, Katleen, Gilon, Patrick, Cuypers, Eva, Tytgat, Jan, Mathieu, Chantal, Schuit, Frans, Rorsman, Patrik, Talavera, Karel, Voets, Thomas, Vennekens, Rudi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380970/
https://ncbi.nlm.nih.gov/pubmed/28361903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14733
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