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Structure Activity Related, Mechanistic, and Modeling Studies of Gallotannins containing a Glucitol-Core and α–Glucosidase

Gallotannins containing a glucitol core, which are only produced by members of the maple (Acer) genus, are more potent α-glucosidase inhibitors than the clinical drug, acarbose. While this activity is influenced by the number of substituents on the glucitol core (e.g. more galloyl groups leads to in...

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Detalhes bibliográficos
Publicado no:RSC Adv
Main Authors: Ma, Hang, Wang, Ling, Niesen, Daniel B., Cai, Ang, Cho, Bongsup P., Tan, Wen, Gu, Qiong, Xu, Jun, Seeram, Navindra P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792293/
https://ncbi.nlm.nih.gov/pubmed/26989482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5RA19014B
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