Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness

Breast tumor progression is accompanied by changes in the surrounding extracellular matrix (ECM) that increase stiffness of the microenvironment. Mammary epithelial cells engage regulatory pathways that permit dynamic responses to mechanical cues from the ECM. Here, we identify a SLIT2/ROBO1 signali...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Le, Lily Thao-Nhi, Cazares, Oscar, Mouw, Janna K., Chatterjee, Sharmila, Macias, Hector, Moran, Angel, Ramos, Jillian, Keely, Patricia J., Weaver, Valerie M., Hinck, Lindsay
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792073/
https://ncbi.nlm.nih.gov/pubmed/26975850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201507054
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