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Beta-adrenergic receptor agonist decreases VEGF levels through altered eNOS and PKC signaling in diabetic retina

Vascular endothelial cell growth factor (VEGF) is increased in diabetic macular edema. Compound 49b, a novel β-adrenergic receptor agonist, is protective in a type 1 diabetic rat model. We questioned whether Compound 49b could decrease VEGF levels, suggesting that Compound 49b may be effective again...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Growth Factors
Hauptverfasser: Jiang, Youde, Zhang, Qiuhua, Steinle, Jena J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791949/
https://ncbi.nlm.nih.gov/pubmed/26115368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977194.2015.1054990
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