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Intravitreal Injection of IGFBP-3 Restores Normal Insulin Signaling in Diabetic Rat Retina

Diabetes-induced changes in growth factor binding protein 3 (IGFBP-3) and tumor necrosis factor alpha (TNFα) have been linked to decreased insulin receptor signaling in diabetic retinopathy. Our previous studies in retinas of diabetic rats have shown that Compound 49b, a novel β-adrenergic receptor...

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Detalhes bibliográficos
Main Authors: Jiang, Youde, Zhang, Qiuhua, Steinle, Jena J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973588/
https://ncbi.nlm.nih.gov/pubmed/24695399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093788
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