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Identification and Validation of Loa loa Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays

Immunoassays are currently needed to quantify Loa loa microfilariae (mf). To address this need, we have conducted proteomic and bioinformatic analyses of proteins present in the urine of a Loa mf-infected patient and used this information to identify putative biomarkers produced by L. loa mf. In tot...

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Bibliographische Detailangaben
Veröffentlicht in:mBio
Hauptverfasser: Drame, Papa M., Meng, Zhaojing, Bennuru, Sasisekhar, Herrick, Jesica A., Veenstra, Timothy D., Nutman, Thomas B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Microbiology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791851/
https://ncbi.nlm.nih.gov/pubmed/26884435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02132-15
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