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Identification and Validation of Loa loa Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays

Immunoassays are currently needed to quantify Loa loa microfilariae (mf). To address this need, we have conducted proteomic and bioinformatic analyses of proteins present in the urine of a Loa mf-infected patient and used this information to identify putative biomarkers produced by L. loa mf. In tot...

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Detalles Bibliográficos
Publicado en:mBio
Main Authors: Drame, Papa M., Meng, Zhaojing, Bennuru, Sasisekhar, Herrick, Jesica A., Veenstra, Timothy D., Nutman, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791851/
https://ncbi.nlm.nih.gov/pubmed/26884435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02132-15
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