Hierarchically-coupled hidden Markov models for learning kinetic rates from single-molecule data

We address the problem of analyzing sets of noisy time-varying signals that all report on the same process but confound straightforward analyses due to complex inter-signal heterogeneities and measurement artifacts. In particular we consider single-molecule experiments which indirectly measure the d...

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Bibliographic Details
Published in:JMLR Workshop Conf Proc
Main Authors: van de Meent, Jan-Willem, Bronson, Jonathan E., Wood, Frank, Gonzalez, Ruben L., Wiggins, Chris H.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791173/
https://ncbi.nlm.nih.gov/pubmed/26985282
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