ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex

We recently identified a previously unidentified sphingosine-1-phosphate (S1P) signaling mechanism that stimulates production of a key innate immune element, cathelicidin antimicrobial peptide (CAMP), in mammalian cells exposed to external perturbations, such as UVB irradiation and other oxidative s...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Park, Kyungho, Ikushiro, Hiroko, Seo, Ho Seong, Shin, Kyong-Oh, Kim, Young il, Kim, Jong Youl, Lee, Yong-Moon, Yano, Takato, Holleran, Walter M., Elias, Peter, Uchida, Yoshikazu
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791017/
https://ncbi.nlm.nih.gov/pubmed/26903652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504555113
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