Successful immunotherapy induces previously unidentified allergen-specific CD4+ T-cell subsets

Allergen immunotherapy can desensitize even subjects with potentially lethal allergies, but the changes induced in T cells that underpin successful immunotherapy remain poorly understood. In a cohort of peanut-allergic participants, we used allergen-specific T-cell sorting and single-cell gene expre...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Ryan, John F., Hovde, Rachel, Glanville, Jacob, Lyu, Shu-Chen, Ji, Xuhuai, Gupta, Sheena, Tibshirani, Robert J., Jay, David C., Boyd, Scott D., Chinthrajah, R. Sharon, Davis, Mark M., Galli, Stephen J., Maecker, Holden T., Nadeau, Kari C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780622/
https://ncbi.nlm.nih.gov/pubmed/26811452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520180113
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