ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex

We recently identified a previously unidentified sphingosine-1-phosphate (S1P) signaling mechanism that stimulates production of a key innate immune element, cathelicidin antimicrobial peptide (CAMP), in mammalian cells exposed to external perturbations, such as UVB irradiation and other oxidative s...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Park, Kyungho, Ikushiro, Hiroko, Seo, Ho Seong, Shin, Kyong-Oh, Kim, Young il, Kim, Jong Youl, Lee, Yong-Moon, Yano, Takato, Holleran, Walter M., Elias, Peter, Uchida, Yoshikazu
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2016
Sujets:
PNAS Plus
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791017/
https://ncbi.nlm.nih.gov/pubmed/26903652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504555113
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires