Beyond Help: Direct Effector Functions of Human Immunodeficiency Virus Type 1-Specific CD4(+) T Cells

The immune correlates of protection in human immunodeficiency virus type 1 (HIV-1) infection remain poorly defined, particularly the contribution of CD4(+) T cells. Here we explore the effector functions of HIV-1-specific CD4(+) T cells. We demonstrate HIV-1 p24-specific CD4(+)-T-cell cytolytic acti...

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Detalhes bibliográficos
Main Authors: Norris, Philip J., Moffett, Howell F., Yang, Otto O., Kaufmann, Daniel E., Clark, Margaret J., Addo, Marylyn M., Rosenberg, Eric S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC479080/
https://ncbi.nlm.nih.gov/pubmed/15280492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8844-8851.2004
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