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Human Immunodeficiency Virus Type 1-Specific CD8(+) T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4(+) T Cells
Primary HIV-1 infection (PHI) is marked by a flu-like syndrome and high levels of viremia that decrease to a viral set point with the first emergence of virus-specific CD8(+) T-cell responses. Here, we investigated in a large cohort of 527 subjects the immunodominance pattern of the first virus-spec...
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708622/ https://ncbi.nlm.nih.gov/pubmed/19458000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00182-09 |
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