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Fibrin matrices enhance the transplant and efficacy of cytotoxic stem cell therapy for post-surgical cancer

Tumor-homing cytotoxic stem cell (SC) therapy is a promising new approach for treating the incurable brain cancer glioblastoma (GBM). However, problems of retaining cytotoxic SCs within the post-surgical GBM resection cavity are likely to significantly limit the clinical utility of this strategy. He...

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Détails bibliographiques
Publié dans:Biomaterials
Auteurs principaux: Bagó, Juli R., Pegna, Guillaume J., Okolie, Onyi, Hingtgen, Shawn D.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790749/
https://ncbi.nlm.nih.gov/pubmed/26803410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.01.007
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