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Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

High levels of extracellular K+ ensure proper development and prolong survival of cerebellar granule neurons in culture. We find that when switched from a culture medium containing high K+ (25 mM) to one containing a low but more physiological K+ concentration (5 mM), differentiated granule neurons...

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Библиографические подробности
Главные авторы: D'Mello, S R, Galli, C, Ciotti, T, Calissano, P
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC47907/
https://ncbi.nlm.nih.gov/pubmed/8248201
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