HISTONE DEACETYLASES AS TARGETS FOR THE TREATMENT OF HUMAN NEURODEGENERATIVE DISEASES

Por D’Mello, Santosh R.
Publicado em 2009

Neuroprotection by Histone Deacetylase-7 (HDAC7) Occurs by Inhibition of c-jun Expression through a Deacetylase-independent Mechanism

Por Ma, Chi, D'Mello, Santosh R.
Publicado em 2011

JAZ (Znf346), a SIRT1-interacting Protein, Protects Neurons by Stimulating p21 (WAF/CIP1) Protein Expression

Por Mallick, Sathi, D'Mello, Santosh R.
Publicado no J Biol Chem (2014)

Cell and Context-Dependent Effects of the Heat Shock Protein DNAJB6 on Neuronal Survival

Por Smith, Chad, D’Mello, Santosh R.
Publicado no Mol Neurobiol (2015)

Polydactyly in Mice Lacking HDAC9/HDRP

Por Morrison, Brad E., D’Mello, Santosh R.
Publicado em 2008

Selective Toxicity by HDAC3 in Neurons: Regulation by Akt and GSK3β

Por Bardai, Farah H., D'Mello, Santosh R.
Publicado em 2011

Insights into the regulation of neuronal viability by nucleophosmin/B23

Por Pfister, Jason A, D’Mello, Santosh R
Publicado no Exp Biol Med (Maywood) (2015)

Induction of Neuronal Cell Death by Paraneoplastic Ma1 Antigen

Por Chen, Huai-Lu, D’Mello, Santosh R.
Publicado no J Neurosci Res (2010)

Regulation of Neuronal Survival by Nucleophosmin 1 (NPM1) Is Dependent on Its Expression Level, Subcellular Localization, and Oligomerization Status

Por Pfister, Jason A., D'Mello, Santosh R.
Publicado no J Biol Chem (2016)

Complex neuroprotective and neurotoxic effects of histone deacetylases

Por Thomas, Elizabeth A., D’Mello, Santosh R.
Publicado no J Neurochem (2018)

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

Por D'Mello, S R, Galli, C, Ciotti, T, Calissano, P
Publicado em 1993

Conditional Deletion of Histone Deacetylase-4 in the Central Nervous System Has No Major Effect on Brain Architecture or Neuronal Viability

Por Price, Valerie, Wang, Lulu, D’Mello, Santosh R.
Publicado em 2012

Epigenetics, Autism Spectrum, and Neurodevelopmental Disorders

Por Rangasamy, Sampathkumar, D’Mello, Santosh R., Narayanan, Vinodh
Publicado em 2013

CLASS IIA HDACS IN THE REGULATION OF NEURODEGENERATION

Por Majdzadeh, Nazanin, Morrison, Brad E., D'Mello, Santosh R.
Publicado em 2008

A chemical compound commonly used to inhibit PKR, {8-(imidazol-4-ylmethylene)-6H-azolidino[5,4-g]benzothiazol-7-one}, protects neurons by inhibiting cyclin-dependent kinase

Por Chen, Hsin-Mei, Wang, Lulu, D’Mello, Santosh R.
Publicado em 2008

Featured Article: Transcriptome profiling of expression changes during neuronal death by RNA-Seq

Por Sharma, Dharmendra, Kim, Min Soo, D’Mello, Santosh R
Publicado no Exp Biol Med (Maywood) (2015)

Catalytic-independent neuroprotection by SIRT1 is mediated through interaction with HDAC1

Por Pfister, Jason A., Ma, Chi, D’Mello, Santosh R.
Publicado no PLoS One (2019)

c-Fos Protects Neurons Through a Noncanonical Mechanism Involving HDAC3 Interaction: Identification of a 21-Amino Acid Fragment with Neuroprotective Activity

Por Rawat, Varun, Goux, Warren, Piechaczyk, Marc, D’Mello, Santosh R.
Publicado no Mol Neurobiol (2015)

Transducin-like Enhancer of Split-1 (TLE1) Combines with Forkhead Box Protein G1 (FoxG1) to Promote Neuronal Survival

Por Dastidar, Somasish Ghosh, Narayanan, Sriram, Stifani, Stefano, D'Mello, Santosh R.
Publicado em 2012

HSF1 Protects Neurons through a Novel Trimerization- and HSP-Independent Mechanism

Por Verma, Pragya, Pfister, Jason A., Mallick, Sathi, D'Mello, Santosh R.
Publicado em 2014