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HSF1 Protects Neurons through a Novel Trimerization- and HSP-Independent Mechanism
Heat shock factor 1 (HSF1) protects neurons from death caused by the accumulation of misfolded proteins. It is believed that this protective effect is mediated by the transcriptional stimulation of genes encoding heat shock proteins (HSPs), a family of chaperones that refold or degrade misfolded pro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905136/ https://ncbi.nlm.nih.gov/pubmed/24478344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3039-13.2014 |
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