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HSF1 Protects Neurons through a Novel Trimerization- and HSP-Independent Mechanism

Heat shock factor 1 (HSF1) protects neurons from death caused by the accumulation of misfolded proteins. It is believed that this protective effect is mediated by the transcriptional stimulation of genes encoding heat shock proteins (HSPs), a family of chaperones that refold or degrade misfolded pro...

詳細記述

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書誌詳細
主要な著者: Verma, Pragya, Pfister, Jason A., Mallick, Sathi, D'Mello, Santosh R.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905136/
https://ncbi.nlm.nih.gov/pubmed/24478344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3039-13.2014
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