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HSF1 Protects Neurons through a Novel Trimerization- and HSP-Independent Mechanism

Heat shock factor 1 (HSF1) protects neurons from death caused by the accumulation of misfolded proteins. It is believed that this protective effect is mediated by the transcriptional stimulation of genes encoding heat shock proteins (HSPs), a family of chaperones that refold or degrade misfolded pro...

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Bibliografiska uppgifter
Huvudupphovsmän: Verma, Pragya, Pfister, Jason A., Mallick, Sathi, D'Mello, Santosh R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905136/
https://ncbi.nlm.nih.gov/pubmed/24478344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3039-13.2014
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