Analysis of Integration Sites of Jaagsiekte Sheep Retrovirus in Ovine Pulmonary Adenocarcinoma

Ovine pulmonary adenocarcinoma (OPA) is an infectious lung tumor of sheep caused by Jaagsiekte sheep retrovirus (JSRV). To test the hypothesis that JSRV insertional mutagenesis is involved in the oncogenesis of OPA, we cloned and characterized 70 independent integration sites from 23 cases of OPA. M...

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Pubblicato in:	J Virol
Autori principali:	Cousens, Christina, Bishop, Jeanette V., Philbey, Adrian W., Gill, Clare A., Palmarini, Massimo, Carlson, Jonathan O., DeMartini, James C., Sharp, J. Michael
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Transformation and Oncogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479065/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15280459/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.16.8506-8512.2004
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