Analysis of Integration Sites of Jaagsiekte Sheep Retrovirus in Ovine Pulmonary Adenocarcinoma

Ovine pulmonary adenocarcinoma (OPA) is an infectious lung tumor of sheep caused by Jaagsiekte sheep retrovirus (JSRV). To test the hypothesis that JSRV insertional mutagenesis is involved in the oncogenesis of OPA, we cloned and characterized 70 independent integration sites from 23 cases of OPA. M...

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Hlavní autoři: Cousens, Christina, Bishop, Jeanette V., Philbey, Adrian W., Gill, Clare A., Palmarini, Massimo, Carlson, Jonathan O., DeMartini, James C., Sharp, J. Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Transformation and Oncogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC479065/
https://ncbi.nlm.nih.gov/pubmed/15280459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8506-8512.2004
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