Analysis of Integration Sites of Jaagsiekte Sheep Retrovirus in Ovine Pulmonary Adenocarcinoma

Ovine pulmonary adenocarcinoma (OPA) is an infectious lung tumor of sheep caused by Jaagsiekte sheep retrovirus (JSRV). To test the hypothesis that JSRV insertional mutagenesis is involved in the oncogenesis of OPA, we cloned and characterized 70 independent integration sites from 23 cases of OPA. M...

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Detalhes bibliográficos
Main Authors: Cousens, Christina, Bishop, Jeanette V., Philbey, Adrian W., Gill, Clare A., Palmarini, Massimo, Carlson, Jonathan O., DeMartini, James C., Sharp, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC479065/
https://ncbi.nlm.nih.gov/pubmed/15280459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.16.8506-8512.2004
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