Analysis of Integration Sites of Jaagsiekte Sheep Retrovirus in Ovine Pulmonary Adenocarcinoma

Ovine pulmonary adenocarcinoma (OPA) is an infectious lung tumor of sheep caused by Jaagsiekte sheep retrovirus (JSRV). To test the hypothesis that JSRV insertional mutagenesis is involved in the oncogenesis of OPA, we cloned and characterized 70 independent integration sites from 23 cases of OPA. M...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Cousens, Christina, Bishop, Jeanette V., Philbey, Adrian W., Gill, Clare A., Palmarini, Massimo, Carlson, Jonathan O., DeMartini, James C., Sharp, J. Michael
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2004
Sujets:
Transformation and Oncogenesis
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479065/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15280459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.16.8506-8512.2004
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