Ciprofloxacin Affects Host Cells by Suppressing Expression of the Endogenous Antimicrobial Peptides Cathelicidins and Beta-Defensin-3 in Colon Epithelia

Antibiotics exert several effects on host cells including regulation of immune components. Antimicrobial peptides (AMPs), e.g., cathelicidins and defensins display multiple functions in innate immunity. In colonic mucosa, cathelicidins are induced by butyrate, a bacterial fermentation product. Here,...

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Veröffentlicht in:Antibiotics (Basel)
Hauptverfasser: Sarker, Protim, Mily, Akhirunnesa, Mamun, Abdullah Al, Jalal, Shah, Bergman, Peter, Raqib, Rubhana, Gudmundsson, Gudmundur H., Agerberth, Birgitta
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790365/
https://ncbi.nlm.nih.gov/pubmed/27025750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics3030353
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