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Rifampicin Resistance: Fitness Costs and the Significance of Compensatory Evolution

Seventy years after the introduction of antibiotic chemotherapy to treat tuberculosis, problems caused by drug-resistance in Mycobacterium tuberculosis have become greater than ever. The discovery and development of novel drugs and drug combination therapies will be critical to managing these proble...

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Publicado en:Antibiotics (Basel)
Autores principales: Hughes, Diarmaid, Brandis, Gerrit
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790335/
https://ncbi.nlm.nih.gov/pubmed/27029299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics2020206
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