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FADD regulates NF-κB activation and promotes ubiquitination of cFLIP(L) to induce apoptosis

Tumor Necrosis Factor-α canonically induces the activation of NF-κB and associated gene product cellular FLICE-like inhibitory protein (cFLIP(L)) to promote cell survival. Previously, we demonstrated that ectopic expression of the Fas associated death domain (FADD) diminishes the expression of cFLIP...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ranjan, Kishu, Pathak, Chandramani
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789601/
https://ncbi.nlm.nih.gov/pubmed/26972597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22787
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