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Apoptotic potential of Fas-associated death domain on regulation of cell death regulatory protein cFLIP and death receptor mediated apoptosis in HEK 293T cells

Fas-associated death domain (FADD) is a common adaptor molecule which plays an important role in transduction of death receptor mediated apoptosis. The FADD provides DED motif for binding to both procaspase-8 and cFLIP molecules which executes death receptor mediated apoptosis. Dysregulated expressi...

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Autors principals: Ranjan, Kishu, Surolia, Avadhesha, Pathak, Chandramani
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421020/
https://ncbi.nlm.nih.gov/pubmed/22791313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-012-0166-2
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