Myeloid cell-restricted Insulin/IGF-1 receptor deficiency protects against skin inflammation

Myeloid cells are key regulators of tissue homeostasis and disease. Alterations in cell-autonomous Insulin/IGF-1 signaling in myeloid cells have recently been implicated in the development of systemic inflammation and insulin-resistant diabetes mellitus type 2 (DM). Impaired wound healing and inflam...

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Udgivet i:J Immunol
Main Authors: Knuever, Jana, Willenborg, Sebastian, Ding, Xiaolei, Akyüz, Mehmet D., Partridge, Linda, Niessen, Carien M., Brüning, Jens C., Eming, Sabine A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789495/
https://ncbi.nlm.nih.gov/pubmed/26519530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501237
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