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Sample size reassessment for a two-stage design controlling the false discovery rate

Sample size calculations for gene expression microarray and NGS-RNA-Seq experiments are challenging because the overall power depends on unknown quantities as the proportion of true null hypotheses and the distribution of the effect sizes under the alternative. We propose a two-stage design with an...

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Publié dans:Stat Appl Genet Mol Biol
Auteurs principaux: Zehetmayer, Sonja, Graf, Alexandra C., Posch, Martin
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789494/
https://ncbi.nlm.nih.gov/pubmed/26461844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/sagmb-2014-0025
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