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Sample size reassessment for a two-stage design controlling the false discovery rate

Sample size calculations for gene expression microarray and NGS-RNA-Seq experiments are challenging because the overall power depends on unknown quantities as the proportion of true null hypotheses and the distribution of the effect sizes under the alternative. We propose a two-stage design with an...

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Detalles Bibliográficos
Publicado en:Stat Appl Genet Mol Biol
Autores principales: Zehetmayer, Sonja, Graf, Alexandra C., Posch, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789494/
https://ncbi.nlm.nih.gov/pubmed/26461844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/sagmb-2014-0025
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