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Dual Genetic Encoding of Acetyl-lysine and Non-deacetylatable Thioacetyl-lysine Mediated by Flexizyme

Acetylation of lysine residues is an important post-translational protein modification. Lysine acetylation in histones and its crosstalk with other post-translational modifications in histone and non-histone proteins are crucial to DNA replication, DNA repair, and transcriptional regulation. We inco...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Xiong, Hai, Reynolds, Noah M., Fan, Chenguang, Englert, Markus, Hoyer, Denton, Miller, Scott J., Söll, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789153/
https://ncbi.nlm.nih.gov/pubmed/26914285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201511750
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