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Tert-butylhydroquinone Compromises Survival in Murine Experimental Stroke

tert-butylhydroquinone (tBHQ), an Nrf2 signaling pathway inducer that is widely used as a food additive in the U.S., prevents oxidative stress-induced cytotoxicity in neurons. This study assesses the effects of tBHQ on ischemic stroke outcomes in mice. We measured infarct size, neurological deficits...

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Bibliographic Details
Published in:Neurotoxicol Teratol
Main Authors: Sun, Jiahong, Hu, Heng, Ren, Xuefang, Simpkins, James W.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789102/
https://ncbi.nlm.nih.gov/pubmed/26827673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ntt.2016.01.004
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