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Sequential Upregulation of Superoxide Dismutase 2 and Heme Oxygenase 1 by tert-Butylhydroquinone Protects Mitochondria during Oxidative Stress

Oxidative stress is linked to mitochondrial dysfunction in aging and neurodegenerative conditions. The transcription factor nuclear factor E2–related factor 2 (Nrf2)–antioxidant response element (ARE) regulates intracellular antioxidative capacity to combat oxidative stress. We examined the effect o...

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Publicat a:Mol Pharmacol
Autors principals: Sun, Jiahong, Ren, Xuefang, Simpkins, James W.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551047/
https://ncbi.nlm.nih.gov/pubmed/26082377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.098269
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