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Morphine-Induced Preconditioning: Involvement of Protein Kinase A and Mitochondrial Permeability Transition Pore
BACKGROUND: Morphine induces myocardial preconditioning (M-PC) via activation of mitochondrial large conductance Ca(2+)-sensitive potassium (mK(Ca)) channels. An upstream regulator of mK(Ca) channels is protein kinase A (PKA). Furthermore, mK(Ca) channel activation regulates mitochondrial bioenerget...
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Publicado en: | PLoS One |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Public Library of Science
2016
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4788451/ https://ncbi.nlm.nih.gov/pubmed/26968004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151025 |
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