Impact of Mitochondrial Ca(2+)-Sensitive Potassium (mBK(Ca)) Channels in Sildenafil-Induced Cardioprotection in Rats

BACKGROUND: Mitochondrial large-conductance Ca(2+)-sensitive potassium (mBK(Ca)) channels are involved in myocardial ischemic preconditioning. Their role in sildenafil-induced cardioprotection is unknown. We investigated whether sildenafil-induced acute cardioprotection is mediated by activation of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Behmenburg, Friederike, Dorsch, Marianne, Huhn, Ragnar, Mally, David, Heinen, André, Hollmann, Markus W., Berger, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684397/
https://ncbi.nlm.nih.gov/pubmed/26671662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144737
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