Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells

Recent reports have shown that cannabinoid 1 receptors (CB1Rs) are expressed in pancreatic β cells, where they induce cell death and cell cycle arrest by directly inhibiting insulin receptor activation. Here, we report that CB1Rs regulate the expression of the anti-apoptotic protein Bcl-2 and cell c...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Kim, Jihye, Lee, Kyung Jin, Kim, Jung Seok, Rho, Jun Gi, Shin, Jung Jae, Song, Woo Keun, Lee, Eun Kyung, Egan, Josephine M., Kim, Wook
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788443/
https://ncbi.nlm.nih.gov/pubmed/26967640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150981
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