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GC skew is a conserved property of unmethylated CpG island promoters across vertebrates
GC skew is a measure of the strand asymmetry in the distribution of guanines and cytosines. GC skew favors R-loops, a type of three stranded nucleic acid structures that form upon annealing of an RNA strand to one strand of DNA, creating a persistent RNA:DNA hybrid. Previous studies show that GC ske...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4787789/ https://ncbi.nlm.nih.gov/pubmed/26253743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv811 |
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