The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent

The combination of Reverse Transcription (RT) and high-throughput sequencing has emerged as a powerful combination to detect modified nucleotides in RNA via analysis of either abortive RT-products or of the incorporation of mismatched dNTPs into cDNA. Here we simultaneously analyze both parameters i...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hauenschild, Ralf, Tserovski, Lyudmil, Schmid, Katharina, Thüring, Kathrin, Winz, Marie-Luise, Sharma, Sunny, Entian, Karl-Dieter, Wacheul, Ludivine, Lafontaine, Denis L. J., Anderson, James, Alfonzo, Juan, Hildebrandt, Andreas, Jäschke, Andres, Motorin, Yuri, Helm, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787781/
https://ncbi.nlm.nih.gov/pubmed/26365242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv895
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